Dosimetry
Accurate radiation dose assessment is critical for optimizing therapeutic outcomes while minimizing toxicity. Our comprehensive dosimetry services provide the quantitative foundation for successful clinical translation.
Dosimetry Capabilities
Quantitative radiation dose assessment using multiple validated approaches
Image-based dosimetryImage-based dosimetry
Ex vivo biodistribution analysisEx vivo biodistribution analysis
OLINDA/EXM calculationsOLINDA/EXM calculations
Organ dose estimatesOrgan dose estimates
Therapeutic index optimizationTherapeutic index optimization
Time-activity curve generationTime-activity curve generation
Tumor-to-organ ratiosTumor-to-organ ratios
Red marrow dosimetryRed marrow dosimetry
Human dose projectionsHuman dose projections
Our Dosimetry Workflow
A streamlined approach to deliver accurate results on time
Data Collection
Biodistribution data is gathered from imaging studies or tissue harvest at multiple time points.
Kinetic Modeling
Time-activity curves are generated and fitted to pharmacokinetic models for each organ of interest.
Dose Calculation
Using validated methods, we calculate absorbed doses to tumors and critical organs.
Analysis Report
Comprehensive dosimetry report with therapeutic indices and recommendations for clinical translation.
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Comprehensive capabilities for your complete radiopharmaceutical development journey
